| Formula |
CAS |
| C4H4ClNOS |
26172-55-4 |
Background5-Chloro-2-methyl-4-isothiazolin-3-one
is a member of the chemically related Isothiazolinone group of preservatives.
It is generally combined with 2-methyl-4-isothiazolin-3-one when used (MCI/MI)
(Kathon CG). The isothiazolinone preservatives include: 2-n-Octyl-4-isothiazolin-3-one,
1,2-Benzisothiazolin-3-one, 2-methyl-4-isothiazolin-3-one, and 5-Chloro-2-methyl-4-isothiazolin-3-one.
Synonyms2-methyl-4-isothiazolin-3-one
5-Chloro-2-methyl-4-isothiazolin-3-one
Acticide
Algucid CH50
Amerstat 250
Euxyl K 100
Cl+Me-isothiazolinone
Fennosan IT 21
Grotan K
Grotan TK2
GR 856 Izolin
Kathon 886 MW
Kathon CG
Kathon DP
Kathon LX
Kathon UT
Kathon WT
Mergal K7
Metat GT
Metatin GT
Methylchloroisothiazolinone/Methylisothiazolinone
Mitco CC 32 L
Paretol
Parmetol DF 35, -DF 12, -A23, -K50, -K40, -DF 18
P3 Multan D
Piror P109
Special Mx 323
Uses
Adhesives/glues
Binders
Bubble baths
Cleaning agents
Cooling tower
water
Cosmetics, especially shampoos
Curing agents
Detergents
Fabric
softeners
Fillings
Hair and body gels
Household cleaning products
Jet fuels
Latex emulsions
Mascaras
Metalworking fluids
Milk sampling
Moist toilet paper
Oil and cooling fluids
Paints
Pesticides
Sanitation
products
Pigments
Polishes
Preservatives
Printing inks
Radiography
Shampoos
Slime control in paper mills
Soaps
Cross-Reactions
Unusual ReactionsAirborne contact dermatitis
Back to list of contact allergens
Referenties
| 1. |
de Groot AC, Liem DH, Weyland JW. Kathon
CG: cosmetic allergy and patch test sensitization. Contact Dermatitis
1985 Feb;12(2):76-80. |
| 2. |
Bruze M, Dahlquist I, Fregert S, Gruvberger
B, Persson K. Contact allergy to the active ingredients of Kathon
CG. Contact Dermatitis 1987 Apr;16(4):183-188. |
| 3. |
Bruze M, Fregert S, Gruvberger B, Persson
K. Contact allergy to the active ingredients of Kathon CG in the
guinea pig. Acta Derm Venereol 1987;67(4):315-320. |
| 4. |
de Groot AC, Weyland JW. Kathon CG: a review.
J Am Acad Dermatol 1988 Feb;18(2 Pt 1):350-358. |
| 5. |
Bruze M, Gruvberger B, Hradil E. Occupational
allergic contact dermatitis due to methylisothiazolinones in a cleansing
cream. Contact Dermatitis 1990 Apr;22(4):235-237. |
| 6. |
Rietschel RL, Nethercott JR, Emmett EA, Maibach
HI, Storrs FJ, Larsen WG, Adams RM, Taylor JS, Marks JG Jr, Mitchell
JC, et al. Methylchloroisothiazolinone-methylisothiazolinone reactions
in patients screened for vehicle and preservative hypersensitivity.
J Am Acad Dermatol 1990 May;22(5 Pt 1):734-748. |
| 7. |
Menné T, Frosch PJ, Veien NK, Hannuksela
M, Björkner B, Lachapelle JM, White IR, Vejlsgaard G, Schubert HJ,
Andersen KE, et al. Contact sensitization to 5-chloro-2-methyl-4-isothiazolin-3-one
and 2-methyl-4-isothiazolin-3-one (MCI/MI). A European multicentre
study. Contact Dermatitis 1991 May;24(5):334-341. |
Auteur(s):dr. Jan R. Mekkes. Dermatoloog, Amsterdam
UMC.
ICD10: L23.9