|
Formula |
CAS |
|
C7H6O2 |
65-85-0 |
CAS: Chemical Abstract Service Registry Number
Background
Benzoic acid is a preservative and anti-fungal agent. It occcurs in nature in free and combined forms. Gum benzoin may contain as much as 20% benzoic acid. It is used with salicylic acid as a topical antifungal. Benzoic acid is involved in non-immunologic contact urticaria and type IV contact allergic reactions.
Synonyms
Benzenecarboxylic acid
Benzoëzuur
E210
Diacylic acid
Phenylfromic acid
Uses
Foods and fruit juices
Topical and systemic medications
Cosmetics
Curing tobacco
Fats
Mordant in calico printing
Cross-Reactions
Benzoic acid along with compounds of the fragrance mix can be found in Balsam of Peru explaining cross-reactions between the two.
Unusual Reactions
Immunologic contact urticaria.
Benzoyl peroxide, used for acne vulgaris, is metabolized in the skin to benzoic acid. Positive patch tests to benzoyl peroxide may be explained by a contact allergy to benzoic acid.
Productkenmerken (Summary in Dutch)
Benzoic acid (benzoëzuur) is een conserveringsmiddel. Producten waar het in zit:
Fruit
abrikozen, bananen, bosbessen, cranberries,
frambozen, grapefruits, kersen, mandarijnen, pruimen, sinaasappels, zwarte bessen
Groenten
groene erwten, knoflook, uien
Vleeswaren
ham, casselerib, katenspek, leverworst, filet américain
Salades
aardappel-, krab-, eier-, fruit-, garnalen-, huzaren-, kip-, komkommer-, rundvlees-, selerie-, tonijn-, vlees-, zalm- en ham-preisalade
Dranken
abrikozenlikeur, bessenjenever, bier, brandy, cola, kersenlikeur, limonadesiroop, pruimenlikeur, roosvicee, sinas, tonic
Zuivel
cheddar-kas, cottage-kaas, crème fraiche, karnemelk, (fruit)kwark, mozarella-kaas, smeerkaas, (vruchten)yoghuert, zure room
Vis
ansjovis, haring (verpakt), garnalen (verpakt), mosselen (verpakt), sardines (verpakt), tonijn in blik, zalm in blik
Sauzen
fritessaus, mayonaise, slasaus, diverse kant-en-klaar sauzen, ketjap, tomatenketchup
Gebak en koekjes
appelgebakjes, gevulde koek, mergpijpjes, gevulde speculaas
Tandpasta's
zendium, prodent actifluor, aqua fresh, odol mondwater
Zalven en crèmes
miconazol(nitraat)crème, -spray en -lotion, pevaryl crème en emulsie, whitfield crème, zalf en lotion, paraffine-emulsie (Agarol)
Overig
asacol klysma, listerine spoelvloeistof, zymafluor druppels, broomhexidinedrank (Bisolvon, Famel), diazepam klysma en injectievloeistof (Stesolid, Valium), Makatussin (forte) druppels, Prozac stroop, Importal drank, Risperdal drank, acidum
formicum injectievloeistof
References
|
1. |
Clemmensen, O. and N. Hjorth, Perioral contact urticaria from sorbic acid and benzoic acid in a salad dressing. Contact Dermatitis, 1982. 8(1): p. 1-6. |
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2. |
Lahti, A. and H.I. Maibach, Long refractory period after one application of nonimmunologic contact urticaria agents to the guinea pig ear. Journal of the American Academy of Dermatology, 1985. 13(4): p. 585-9. |
|
3. |
Lahti, A. and H.I. Maibach, Species specificity of nonimmunologic contact urticaria: guinea pig, rat, and mouse. Journal of the American Academy of Dermatology, 1985. 13(1): p. 66-9. |
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4. |
Larmi, E., A. Lahti, and M. Hannuksela, Immediate contact reactions to benzoic acid and the sodium salt of pyrrolidone carboxylic acid. Comparison of various skin sites. Contact Dermatitis, 1989. 20(1): p. 38-40. |
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5. |
Rademaker, M. and A. Forsyth, Contact dermatitis in children. Contact Dermatitis, 1989. 20(2): p. 104-7. |
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6. |
Lahti, A., A.M. Poutiainen, and M. Hannuksela, Alcohol vehicles in tests for non-immunological immediate contact reactions. Contact Dermatitis, 1993. 29(1): p. 22-5. |
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7. |
Koopmans AK, Bruynzeel DP. Benzoëzuur: plakproef-reacties. Ned. Tijdschr Dermatol Venereol 1999;9:286-288 |
13-06-2011
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