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Formula |
CAS |
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C25H34O6 |
51333-22-3 |
CAS: Chemical Abstract Service Registry Number
Background
Budesonide is a nonhalogenated corticosteroid for use in topical preparations and for the treatment of rhinitis and asthma.
Synonyms
Budesonide
16,17-Butylidenebis(oxy)-11-,21-dihydroxypregna-1,4-diene-3,20-dione
(R,S)-11b,16a,17,21,tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with butyraldehyde
S-1320
Budeson
Preferid
Pulmicort
Rhinocort
Spirocort
Uses
Anti-inflammatory agent
Nasal spray
Cross-Reactions
It belongs to the group B (triamcinolone acetonide) grouping of corticosteroids (Coopman et al). According the A-D grouping, patch-test reactions occur 6-7 times more frequently within well-defined groups of structurally related chemicals than between corticosteroids of different groups.
Unusual Reactions
References
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1. |
van Hecke, E. and L. Temmerman, Contact allergy to the corticosteroid budesonide. Contact Dermatitis, 1980. 6(7): p. 509. |
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2. |
Meding, B. and E. Dahlberg, Contact allergy to budesonide in a nasal spray. Contact Dermatitis, 1986. 14(4): p. 253-4. |
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3. |
Coopman, S., H. Degreef, and A. Dooms-Goossens, Identification of cross-reaction patterns in allergic contact dermatitis from topical corticosteroids. British Journal of Dermatology, 1989. 121(1): p. 27-34. |
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4. |
Jerez, J., et al., Allergic contact dermatitis from budesonide. Contact Dermatitis, 1990. 22(4): p. 231-2. |
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5. |
Gamboa, P.M., I. Jauregui, and I. Antepara, Contact dermatitis from budesonide in a nasal spray without cross-reactivity to amcinonide. Contact Dermatitis, 1991. 24(3): p. 227-8. |
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6. |
Hayakawa, R., et al., Allergic contact dermatitis due to budesonide. Contact Dermatitis, 1991. 24(2): p. 136-7. |
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7. |
Noda, H., et al., Contact dermatitis due to budesonide [published erratum appears in Contact Dermatitis 1992 Jan;26(1):71]. Contact Dermatitis, 1991. 25(1): p. 72-3. |
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8. |
Peris-Tortajada, A., et al., Contact allergy to topical budesonide. Journal of Allergy & Clinical Immunology, 1991. 87(2): p. 597-8. |
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9. |
Piraccini, B.M., et al., Contact dermatitis due to budesonide. Contact Dermatitis, 1991. 24(1): p. 54-5. |
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10. |
Burden, A.D. and M.H. Beck, Contact hypersensitivity to topical corticosteroids. British Journal of Dermatology, 1992. 127(5): p. 497-500. |
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11. |
Dooms-Goossens, A. and M. Morren, Results of routine patch testing with corticosteroid series in 2073 patients. Contact Dermatitis, 1992. 26(3): p. 182-91. |
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12. |
Faria, A., J. Marote, and C. de Freitas, Contact allergy to budesonide in a nasal spray. Contact Dermatitis, 1992. 27(1): p. 57. |
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13. |
Hayakawa, R., et al., A case of budesonide contact allergy. Contact Dermatitis, 1992. 26(2): p. 128-9. |
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14. |
Wilkinson, S.M., A.G. Smith, and J.S. English, Erythroderma following the intradermal injection of the corticosteroid budesonide. Contact Dermatitis, 1992. 27(2): p. 121-2. |
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15. |
Noda, H., et al., Contact sensitivity and cross-reactivity of budesonide. Contact Dermatitis, 1993. 28(4): p. 212-5. |
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16. |
Veraldi, S., D. Fallahdar, and A. Riboldi, Allergic contact dermatitis from budesonide. Contact Dermatitis, 1993. 28(2): p. 116. |
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17. |
Corazza, M., et al., Compound allergy to topical budesonide. Contact Dermatitis, 1994. 30(4): p. 246-7. |
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18. |
Iglesias-Cadarso, A., et al., Allergic contact dermatomucositis to budesonide. Journal of Allergy & Clinical Immunology, 1994. 94(3 Pt 1): p. 559-60. |
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19. |
Jorro, G., et al., Contact allergy to topical budesonide in nasal spray. Contact Dermatitis, 1993. 28(4): p. 254. |
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20. |
Okano, M., Contact dermatitis due to budesonide: report of five cases and review of the Japanese literature. International Journal of Dermatology, 1994. 33(10): p. 709-15. |
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21. |
Lepoittevin, J.P., J. Drieghe, and A. Dooms-Goossens, Studies in patients with corticosteroid contact allergy. Understanding cross-reactivity among different steroids [see comments]. Archives of Dermatology, 1995. 131(1): p. 31-7. |
19-06-2011
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