Formula |
CAS |
C10H9Cl4NO2S |
2425-06-1 |
CAS: Chemical Abstract Service Registry Number
Background
Captafol is an agricultural fungicide used especially in potatoes. The
EPA has determined that captafol is oncogenic in mice and rats.
Synonyms
Captafol
Difolatan®
3a,4,7,7a-Tetrahydro-2-[(1,1,2,2-tetrachloroethyl)thio]-1H-isoindole-1,3(2H)-dione
N-(1,1,2,-tetrachloroethylthio)-4-cyclohexene-1,2-dicarboximide
N-(1,1,2,2-tetrachloroethylmercapto)-4-cyclohexene-1,2-dicarboximide
N-(1,1,2,2-Tetrachloroethylthio)-D4-tetrahydrophthalimide
N-(1,1,2,2-Tetrachloroethylsulfenyl)-cis-4-cyclohexene-1,2-dicarboximide
Uses
Agriculture
Pesticide
Cross-Reactions
Unusual Reactions
References
1.
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Groundwater, J.R.,
Difolatan dermatitis in a welder; non-agricultural
exposure. Contact Dermatitis, 1977. 3(2): p. 104.
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2.
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Stoke,
J.C., Captafol dermatitis in the timber industry.
Contact Dermatitis, 1979. 5(5): p. 284-92.
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3.
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Matsushita,
T., S. Nomura, and T. Wakatsuki, Epidemiology of
contact dermatitis from pesticides in Japan. Contact Dermatitis, 1980. 6(4): p. 255-9.
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4.
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Brown,
R., Contact sensitivity to Difolatan (Captafol). Contact
Dermatitis, 1984. 10(3): p. 181-2.
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5.
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Lisi,
P., S. Caraffini, and D. Assalve, A test series for pesticide
dermatitis. Contact Dermatitis, 1986. 15(5): p. 266-9.
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6.
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Lisi,
P., S. Caraffini, and D. Assalve, Irritation and sensitization
potential of pesticides. Contact Dermatitis, 1987. 17(4): p.
212-8.
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7.
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Thiboutot,
D.M., B.H. Hamory, and J.G. Marks, Jr., Dermatoses
among floral shop workers. Journal of the American Academy of Dermatology,
1990. 22(1): p. 54-8.
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8.
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Cushman, J.R. and J.C. Street,
Contact sensitivity to captafol
in BALB/c mice. Contact Dermatitis, 1991. 24(5): p. 363-5.
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17-07-2011
(JRM) - www.huidziekten.nl
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