|
Formula |
CAS |
|
C19H38N2O3 |
61789-40-0 |
CAS: Chemical Abstract Service Registry Number
Background
Cocamidopropyl betaine (CAPB) is an increasingly used surfactant in shampoos,
detergents, and cleansing lotions. CAPB is an alkylamidobetaine and functions
as an amphoteric surfactant with anionic and cationic properties depending
on pH. Betaines are less foaming than other surfactants and are expensive;
however, they are relatively gentle to the skin, have a low potential to
irritate the eyes, have good conditioning characteristics, and have antibacterial
activity. A number of cases of contact allergy to CAPB
has been reported in the past several years. In 1200 consecutive patch-test
clinic patients, 46 patients (3.8%) had allergic reactions.
3-dimethylaminopropylamine (DMAPA), an aliphatic amine used to synthesize
CAPB, has been reported to be the responsible allergen in the CAPB reactions (Angelini et al; Pigatto et al).
Related compound: lauryl hydroxysultaine (SHD), synonyme: Cocoamidopropyl Hydroxy Sulfo Betaine (CHSB), Formula:
RCONH (CH2)3N+(CH3)2CH2CH(OH)CH2SO3- R: Coco, CAS-nr: 86438-79-1.
Synonyms
Tegobetaine L7
N-Cocamidopropyl-N,N-dimethylglycine inner salt; N-(3-Cocoamidopropyl)-betaine
CAPB
Cocoyl amide propyldimethyl glycine
Coconut oil amidopropyl betaine
Uses
Anal detergent
Bath formulations
Contact lens cleaning solutions
Creams
Deodorants
Eye make-up removers
Hair colorants and styling products
Liquid soaps
Shampoos
Shaving products
Toothpastes
Cross-Reactions
Cocobetaine
Triethanolamine polyethylene glycol cocamide sulfate
3-dimethylaminopropylamine
Unusual Reactions
Productkenmerken (Summary in Dutch)
Cocamidopropyl betaïne is een schuimvormend middel. Het is onderdeel van allerlei shampoos en zepen. Dit soort chemische stoffen worden ook wel surfactans genoemd (oppervlaktespanning verlagend middel). Het zorgt ervoor dat cosmetica een mooi schuimlaagje vormen, en het zit bijvoorbeeld in scheerschuimen en bad - en douche gels. In alle producten die schuimen kan cocamidopropyl betaïne zitten. Over het algemeen is het een mild en huid-vriendelijk product, het zit bijvoorbeeld ook in kindershampoos. Maar bij sommige personen kan het toch een contactallergie veroorzaken. Vooral kappers en medewerkers van schoonheidssalons lopen kans op het ontwikkelen van een contactallergie.
In
de volgende producten kan
Cocamidopropyl betaïne aanwezig zijn:
- shampoos,
kindershampoos
- bad- en douche gels
- vloeibare zepen, vloeibare handzeep, bubbelbadzeep
- reinigende huidlotions, oog make-up removers
- scheerzeep
- contactlens schoonmaak vloeistof
-
tandpasta
- conditioner voor de haren
-
deodorantia
- cosmetica crèmes
-
haarkleurmiddel
- antiseptische middelen
- vochtige doekjes voor reiniging perianale huid
Allergeen testsubstantie: Cocamidopropylbetaine (in water) 1% Van der Bend E2303 (reeks: cosmetics / cosmetica)
References
|
1. |
Andersen KE, Roed-Petersen J, Kamp P. Contact allergy related to TEA-PEG-3 cocamide sulfate and cocamidopropyl betaine in a shampoo. Contact Dermatitis 1984;11(3):192-193. |
|
2. |
Cameli N. et al. Eyelid dermatitis due to cocamidopropyl betaine in a hard contact lens solution. Contact Dermatitis 1991;25(4):261-262. |
|
3. |
Ross JS, White IR. Eyelid dermatitis due to cocamidopropyl betaine in an eye make-up remover. Contact Dermatitis 1991;25(1):64. |
|
4. |
Korting HC. et al. Allergic contact dermatitis to cocamidopropyl betaine in shampoo. Journal of the American Academy of Dermatology 1992;27(6 Pt 1):1013-1015. |
|
5. |
Peter C, Hoting E. Contact allergy to cocamidopropyl betaine (CAPB). Contact Dermatitis 1992;26(4):282-283. |
|
6. |
Taniguchi S. et al. Shampoo dermatitis due to cocamidopropyl betaine. Contact Dermatitis 1992;26(2):139. |
|
7. |
van der Walle HB, Brunsveld VM. Dermatitis in hairdressers. (I). The experience of the past 4 years. Contact Dermatitis 1994;30(4):217-221. |
|
8. |
Pigatto P, Bigardi A, Cusano F. Contact dermatitis to cocamidopropylbetaine is caused by residual amines: Relevance, clinical characteristics, and review of the literature. American Journal of Contact Dermatitis 1995;6(1):13-16. |
21-05-2011
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