Formula |
CAS |
C21H30O5 |
50-23-7 |
CAS: Chemical Abstract Service Registry Number
Background
Hydrocortisone is a low-potency topical and systemic corticosteroid. It
has been classified as group A by Coopman et al. According the A-D grouping,
patch-test reactions occur 6-7 times more frequently within well-defined
groups of structurally related chemicals than between corticosteroids of
different groups.
Synonyms
Hydrocortisone
11,17,21-Trihydroxypregn-4-ene-3,20-dione
Cortisol
4-Pregnen-11b,17a,21-triol-3,20-dione
17-Hydroxycorticosterone
Ala-Cort
Anflam
Cleiton
cremesone
Cobadex
Cort-dome
Cortef
Cortifoam
Cortril
Dermacort
dermolate
Dermolen
Dioderm
Dome-Cort
elcorbin
Efcorlin
EF-Cortelan
Efcortelin
Evacort
Eye-Cort
Epicort
Ficorrtril
Genacort
Hidro-Colisona
HVB
Hydro-Adresson
Hydrocort
Hydrocortisyl
Hydrocortone
Incortin-H
Kendall's compound F
Lubricort
Medicort
Meusicort
Maintasone
Mildison
Reichstein's substance M
schersoson f
Sigmacort
Texacort
Timocort
Proctoscort
Rectoid
Zenoxone
Uses
Glucocorticoid
Corticosteroid
Anti-inflammatory
Pharmaceutical
Cross-Reactions
Tixocortol
Prednisolone
Methylprednisolone
Prednisone
Meprednisone
Unusual Reactions
References
1.
|
Alani, S.D. and M.D.
Alani, Allergic contact dermatitis and conjunctivitis
to corticosteroids. Contact Dermatitis, 1976. 2(6): p. 301-4.
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2.
|
Rietschel,
R.L., Photocontact dermatitis to hydrocortisone.
Contact Dermatitis, 1978. 4(6): p. 334-7.
|
3.
|
Dooms-Goossens, A., et al.,
Contact allergy to hydrocortisone
and thixocortol pivalate: problems in the detection of corticosteroid sensitivity.
Contact Dermatitis, 1986. 14(2): p. 94-102.
|
4.
|
Lindelof, B.,
Contact allergy to hydrocortisone. Contact
Dermatitis, 1988. 18(5): p. 309.
|
5.
|
Coopman, S. and A.
Dooms-Goossens, Cross-reactions in topical
corticosteroid contact dermatitis. Contact Dermatitis, 1988. 19(2):
p. 145-6.
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6.
|
Dooms-Goossens, A.,
Identification of undetected corticosteroid
allergy. Contact Dermatitis, 1988. 18(2): p. 124-5.
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7.
|
Coopman, S., H.
Degreef, and A. Dooms-Goossens, Identification
of cross-reaction patterns in allergic contact dermatitis from topical
corticosteroids. British Journal of Dermatology, 1989. 121(1):
p. 27-34.
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8.
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Dooms-Goossens,
A.E., et al., Contact allergy to corticosteroids:
a frequently missed diagnosis?. Journal of the American Academy of
Dermatology, 1989. 21(3 Pt 1): p. 538-43.
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9.
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Lauerma,
A.I., Screening for corticosteroid contact sensitivity.
Comparison of tixocortol pivalate, hydrocortisone-17-butyrate and hydrocortisone.
Contact Dermatitis, 1991. 24(2): p. 123-30.
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10.
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Lauerma,
A.I., S. Reitamo, and H.I. Maibach, Systemic hydrocortisone/cortisol
induces allergic skin reactions in presensitized subjects. Journal
of the American Academy of Dermatology, 1991. 24(2 Pt 1): p. 182-5.
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11.
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Wilkinson,
S.M. and J.S. English, Hydrocortisone sensitivity.
An investigation into the nature of the allergen. Contact Dermatitis,
1991. 25(3): p. 178-81.
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Wilkinson,
S.M. and J.S. English, Hydrocortisone sensitivity:
a prospective study of the value of tixocortol pivalate and hydrocortisone
acetate as patch test markers. Contact Dermatitis, 1991. 25(2):
p. 132-3.
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13.
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Burden, A.D. and
M.H. Beck, Contact hypersensitivity to topical
corticosteroids. British Journal of Dermatology, 1992. 127(5):
p. 497-500.
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14.
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Schoenmakers, A., et al.,
Corticosteroid or steroid allergy?.
Contact Dermatitis, 1992. 26(3): p. 159-62.
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15.
|
Wilkinson,
S.M. and J.S. English, Hydrocortisone sensitivity:
clinical features of fifty-nine cases. Journal of the American Academy
of Dermatology, 1992. 27(5 Pt 1): p. 683-7.
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16.
|
Rasanen, L. and T.
Hasan, Allergy to systemic and intralesional
corticosteroids. British Journal of Dermatology, 1993. 128(4):
p. 407-11.
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17.
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Torres, V., et al.,
Systemic contact dermatitis from hydrocortisone.
Contact Dermatitis, 1993. 29(2): p. 106.
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18.
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Wilkinson,
S.M., J.S. English, and D.L. Mattey, In vitro evidence
of delayed-type hypersensitivity to hydrocortisone. Contact Dermatitis,
1993. 29(5): p. 241-5.
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19.
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Wilkinson,
S.M., et al., HLA-A, -B and -DR antigens in hydrocortisone
contact hypersensitivity. Contact Dermatitis, 1993. 28(5): p.
295-7.
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20.
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Dooms-Goossens, A., et al.,
Contact allergy to corticosteroids:
the results of a two-centre study. British Journal of Dermatology,
1994. 130(1): p. 42-7.
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21.
|
Wilkinson,
S.M., et al., Immunohistochemical appearance of corticosteroid
contact hypersensitivity reactions. Contact Dermatitis, 1994. 31(5):
p. 304-7.
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22.
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Lepoittevin, J.P., J.
Drieghe, and A. Dooms-Goossens, Studies
in patients with corticosteroid contact allergy. Understanding cross-reactivity
among different steroids [see comments]. Archives of Dermatology, 1995. 131(1):
p. 31-7.
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10-12-2011
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