Formula |
CAS |
C8H8O3 |
99-76-3 |
CAS: Chemical Abstract Service Registry Number
Background
Methyl-4-hydroxybenzoate (methyl paraben) along with the other esters of p-hydroxybenzoate
(parabens) are the most widely used preservatives in
food, drugs, and cosmetics.
Synonyms
4-Hydroxybenzoic acid methyl ester
Methyl-4-hydroxybenzoate
Methyl-p-hydroxybenzoate
Methyl Chemosept
Methyl Parasept
Methylparaben
Nipagin M
Tegosept M
Uses
Beverages
Cosmetics
Creams and lotions
Food (salad dressings, mayonnaise, spiced sauces, mustard, frozen dairy
products, baked products)
Pharmaceuticals
Cross-Reactions
Parabens
Hydroquinoe monobenzylether
Para group of compounds
Unusual Reactions
Immunologic contact urticaria
Nonimmunologic contact urticaria
References
1.
|
Schamberg,
I.L., Allergic contact dermatitis to methyl and propyl
paraben. Archives of Dermatology, 1967. 95(6): p. 626-8.
|
2.
|
Fisher,
A.A., Paraben dermatitis due to a new medicated bandage:
The "paraben paradox". Contact Dermatitis, 1979. 5(4): p. 273-4.
|
3.
|
Fraki,
J.E., L. Peltonen, and V.K. Hopsu-Havu, Allergy to various
components of topical preparations in stasis dermatitis and leg ulcer.
Contact Dermatitis, 1979. 5(2): p. 97-100.
|
4.
|
Henry, J.C.,
E.H. Tschen, and L.E. Becker, Contact urticaria
to parabens. Archives of Dermatology, 1979. 115(10): p. 1231-2.
|
5.
|
Fisher,
A.A., Allergen replacement (alternatives) in the management
of contact dermatitis. Cutis, 1981. 28(4): p. 368-70, 372.
|
6.
|
Adams,
R.M. and H.I. Maibach, A five-year study of cosmetic reactions.
Journal of the American Academy of Dermatology, 1985. 13(6): p.
1062-9.
|
7.
|
Fisher,
A.A., Allergic reactions to contact lens solutions.
Cutis, 1985. 36(3): p. 209-11.
|
8.
|
Menne, T. and N.
Hjorth, Routine patch testing with paraben esters.
Contact Dermatitis, 1988. 19(3): p. 189-91.
|
9.
|
Carradori, S., A.M.
Peluso, and M. Faccioli, Systemic contact
dermatitis due to parabens. Contact Dermatitis, 1990. 22(4):
p. 238-9.
|
10.
|
Seidenari, S., et al.,
Patch and prick test study of 593 healthy
subjects. Contact Dermatitis, 1990. 23(3): p. 162-7.
|
11.
|
Fisher,
A.A., A "current contact news" follow-up: controversial
subjects and those resulting in litigation [news]. Cutis, 1993. 52(5):
p. 254-6.
|
12.
|
Perrenoud, D., et al.,
Frequency of sensitization to 13 common
preservatives in Switzerland. Swiss Contact Dermatitis Research Group.
Contact Dermatitis, 1994. 30(5): p. 276-9.
|
13.
|
Rastogi, S.C., et al.,
Contents of methyl-, ethyl-, propyl-,
butyl- and benzylparaben in cosmetic products. Contact Dermatitis,
1995. 32(1): p. 28-30.
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13-08-2011
(JRM) - www.huidziekten.nl
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