Prilocaine hydrochloride

codes geen / geen

 

 

Formula

CAS

C13H21ClN2O

1786-81-8

 
CAS: Chemical Abstract Service Registry Number
 

Background

Prilocaine hydrochloride belongs to the amide group of local anesthetics and has been used since 1961. Allergic reactions are rare to members of this group of anesthetics. 

 

Synonyms

Citanest
EMLA® cream
Prilocaine hydrochloride
Xylonest
N-(2-Methylphenyl)-2-(propylamino)-propanamide
2-(Propylamino)-o-propionotoluidide
N-(a-propylaminopropionyl)-o-toluidine
a-propylamino-2-methylpropionanilide
Propitocaine

 

Uses

Local anesthetic
EMLA® cream (lidocaine base + prilocaine base)

 

Cross-Reactions

Lidocaine
Bupivacaine
Cinchocaine
Mepivacaine

 

Unusual Reactions

 

 

References

 1.

Fregert, S., E. Tegner, and I. Thelin, Contact allergy to lidocaine. Contact Dermatitis, 1979. 5(3): p. 185-8.

 2.

Curley, R.K., A.W. Macfarlane, and C.M. King, Contact sensitivity to the amide anesthetics lidocaine, prilocaine, and mepivacaine. Case report and review of the literature. Archives of Dermatology, 1986. 122(8): p. 924-6.

 3.

Black, R.J., T.A. Dawson, and W.C. Strang, Contact sensitivity to lignocaine and prilocaine. Contact Dermatitis, 1990. 23(2): p. 117-8.

 4.

van den Hove, J., et al., Allergic contact dermatitis from prilocaine, one of the local anaesthetics in EMLA cream. Contact Dermatitis, 1994. 30(4): p. 239.

 

 

 

 

 

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