Formula |
CAS |
C13H21ClN2O |
1786-81-8 |
CAS: Chemical Abstract Service Registry Number
Background
Prilocaine hydrochloride belongs to the amide group of local anesthetics
and has been used since 1961. Allergic reactions are rare to members of
this group of anesthetics.
Synonyms
Citanest
EMLA® cream
Prilocaine hydrochloride
Xylonest
N-(2-Methylphenyl)-2-(propylamino)-propanamide
2-(Propylamino)-o-propionotoluidide
N-(a-propylaminopropionyl)-o-toluidine
a-propylamino-2-methylpropionanilide
Propitocaine
Uses
Local anesthetic
EMLA® cream (lidocaine base + prilocaine base)
Cross-Reactions
Lidocaine
Bupivacaine
Cinchocaine
Mepivacaine
Unusual Reactions
References
1.
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Fregert, S., E.
Tegner, and I. Thelin, Contact allergy to lidocaine.
Contact Dermatitis, 1979. 5(3): p. 185-8.
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2.
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Curley,
R.K., A.W. Macfarlane, and C.M. King, Contact sensitivity
to the amide anesthetics lidocaine, prilocaine, and mepivacaine. Case report
and review of the literature. Archives of Dermatology, 1986. 122(8):
p. 924-6.
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3.
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Black, R.J.,
T.A. Dawson, and W.C. Strang, Contact sensitivity
to lignocaine and prilocaine. Contact Dermatitis, 1990. 23(2):
p. 117-8.
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4.
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van den Hove, J., et al.,
Allergic contact dermatitis from prilocaine,
one of the local anaesthetics in EMLA cream. Contact Dermatitis, 1994. 30(4):
p. 239.
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08-01-2012
(JRM) - www.huidziekten.nl
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