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Formula |
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CAS: Chemical Abstract Service Registry Number
Background
Propolis is a resinous substance found in bee hives containing flavonoid
aglycones. Propolis is collected by bees from poplar buds. The main allergen
is 1,1-dimethylallyl caffeic acid ester (LB-1). Bee keepers are classically
affected by dermatitis, although propolis has been used by manufacturers
of stringed instruments. The oral ingestion of propolis has caused cheilitis
and perioral dermatitis.
Caffeic acid is isolated from propolis. The residue from the alcohol
extraction is called propolis resin, yielding propolis balsam on extraction
with hot petroleum ether. Propolis balsam has a hyacinth odor and is said
to contain 10% cinnamyl alcohol.
Synonyms
1,1-dimethylallyl caffeic acid ester (LB-1)
Bee bread
Bee glue
Hive doss
Propolis wax
Propolis resin
Propolis balsam
Uses
Biocosmetics
Chewing gum
Chunks for chewing
Face creams
Mouthwash
Ointments
Powders
Tablets
Toothpaste
Violin wax
Wood polish
Wood varnish
Cross-Reactions
Balsam Peru
Unusual Reactions
Airborne contact
References
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1. |
Wanscher, B., Contact dermatitis from propolis. British Journal of Dermatology, 1976. 94(4): p. 451-5. |
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2. |
Petersen, H.O., Hypersensitivity to propolis. Contact Dermatitis, 1977. 3(5): p. 278-9. |
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3. |
Kokelj, F. and G. Trevisan, Contact dermatitis from propolis. Contact Dermatitis, 1983. 9(6): p. 518. |
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4. |
Melli, M.C., S. Giorgini, and A. Sertoli, Occupational dermatitis in a bee-keeper. Contact Dermatitis, 1983. 9(5): p. 427-8. |
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5. |
Monti, M., et al., Occupational and cosmetic dermatitis from propolis. Contact Dermatitis, 1983. 9(2): p. 163. |
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6. |
Rudzki, E. and Z. Grzywa, Dermatitis from propolis. Contact Dermatitis, 1983. 9(1): p. 40-5. |
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7. |
Takahashi, M., I. Matsuo, and M. Ohkido, Contact dermatitis due to honeybee royal jelly. Contact Dermatitis, 1983. 9(6): p. 452-5. |
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8. |
Pincelli, C., A. Motolese, and L. Pincelli, Contact dermatitis from propolis. Contact Dermatitis, 1984. 11(1): p. 49. |
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9. |
Valsecchi, R. and T. Cainelli, Dermatitis from propolis. Contact Dermatitis, 1984. 11(5): p. 317. |
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10. |
Ayala, F., et al., Contact dermatitis from propolis. Contact Dermatitis, 1985. 12(3): p. 181-2. |
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11. |
Machackova, J., Contact dermatitis to propolis. Contact Dermatitis, 1985. 13(1): p. 43-4. |
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12. |
Rudzki, E., Z. Grzywa, and Z. Pomorski, New data on dermatitis from propolis. Contact Dermatitis, 1985. 13(3): p. 198-9. |
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13. |
Tosti, A., et al., Propolis contact dermatitis. Contact Dermatitis, 1985. 12(4): p. 227-8. |
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14. |
Angelini, G., G.A. Vena, and C.L. Meneghini, Psoriasis and contact allergy to propolis. Contact Dermatitis, 1987. 17(4): p. 251-3. |
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15. |
Cirasino, L., A. Pisati, and F. Fasani, Contact dermatitis from propolis. Contact Dermatitis, 1987. 16(2): p. 110-1. |
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16. |
Hausen, B.M., et al., Propolis allergy. (I). Origin, properties, usage and literature review. Contact Dermatitis, 1987. 17(3): p. 163-70. |
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17. |
Hausen, B.M., et al., Propolis allergy. (II). The sensitizing properties of 1,1-dimethylallyl caffeic acid ester. Contact Dermatitis, 1987. 17(3): p. 171-7. |
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18. |
Kleinhans, D., Airborne contact dermatitis due to propolis. Contact Dermatitis, 1987. 17(3): p. 187-8. |
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19. |
Trevisan, G. and F. Kokelj, Contact dermatitis from propolis: role of gastrointestinal absorption. Contact Dermatitis, 1987. 16(1): p. 48. |
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20. |
Young, E., Sensitivity to propolis. Contact Dermatitis, 1987. 16(1): p. 49-50. |
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21. |
Hausen, B.M. and E. Wollenweber, Propolis allergy. (III). Sensitization studies with minor constituents. Contact Dermatitis, 1988. 19(4): p. 296-303. |
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22. |
Machackova, J., The incidence of allergy to propolis in 605 consecutive patients patch tested in Prague. Contact Dermatitis, 1988. 18(4): p. 210-2. |
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23. |
Nakamura, T., Sensitivity to propolis in Japan. Contact Dermatitis, 1988. 18(5): p. 313. |
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24. |
Ginanneschi, M., et al., Propolis allergy: synthesis and patch testing of gamma,gamma-dimethylallyl caffeic acid ester and its o-methyl derivatives. Contact Dermatitis, 1989. 21(4): p. 267-9. |
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25. |
Raton, J.A., A. Aguirre, and J.L. Diaz-Perez, Contact dermatitis from propolis. Contact Dermatitis, 1990. 22(3): p. 183-4. |
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26. |
Hausen, B.M., et al., Propolis allergy (IV). Studies with further sensitizers from propolis and constituents common to propolis, poplar buds and balsam of Peru. Contact Dermatitis, 1992. 26(1): p. 34-44. |
08-01-2012
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