Tetrachlorsalicylanilide (TCS)

codes geen / geen

 

 

Formula

CAS

C13H7Cl4NO2

1154-59-2

 
CAS: Chemical Abstract Service Registry Number
 

Background

Tetrachlorsalicylanilide (TCS) is a bacteriostatic agent banned by the FDA from use in cosmetics. 

 

Synonyms

3,3',4',5-Tetrachlorosalicylanilide
3,5-Dichloro-N-(3,4-dichlorophenyl)-2-hydroxybenzamide
Irgasan BS 200
TCS
Tetrachlorsalicylanilide

 

Uses

Cooling fluids
Deodorants
Polishes
Rinses
Shampoos
Surgical and laurndry soaps
Textile finishes

 

Cross-Reactions

Halogenated salicylanilides
Hexachlorophene

 

Unusual Reactions

Photoallergy
Phototoxicity
Persistent light reaction

 

References

 1.

Kaidbey, K.H. and A.M. Kligman, Photomaximization test for identifying photoallergic contact sensitizers. Contact Dermatitis, 1980. 6(3): p. 161-9.

 2.

Gerberick, G.F. and C.A. Ryan, Contact photoallergy testing of sunscreens in guinea pigs. Contact Dermatitis, 1989. 20(4): p. 251-9.

 3.

Shivji, G.M., W.R. Brown, and C.A. Ramsay, A dose-response study of UVB-induced suppression of contact photosensitivity in the mouse. British Journal of Dermatology, 1990. 122(2): p. 147-52.

 4.

Miyauchi, H. and T. Horio, A new animal model for contact dermatitis: the hairless guinea pig. Journal of Dermatology, 1992. 19(3): p. 140-5.

 

 

 

 

 

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