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Formula |
CAS |
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C9H9HgNaO2S |
54-64-8 |
CAS: Chemical Abstract Service Registry Number
Background
Thiomersal is used as an antiseptic and a preservative in topical medicaments,
cosmetics, and vaccines.
It should be noted that thiomersal contains two distinct radicals,
an organic mercury compound and a thiosalicylate. The allergic reactions
may be from either compound.
Patients sensitive to thiomersal (Merthiolate) can be divided into
three groups: 1) positive to thiomersal but negative to other mercurials
and to thiosalicylic acid; 2) positive to thiomersal and to some other
mercurials but negative to thiosalicylic acid; and 3) positive to thiomersal
and to thiosalicylic acid, but negative to other mercurial
Synonyms
Ethyl [2-mercaptobenzoato(2 ‹)-O,S]-mercurate(1‹) sodium
Ethyl (2-mercaptobenzoato-S) mercury, sodium salt
Mercurothiolate
Merfamin
Merthiolate
Mertorgan
Merzonin
[(o-carboxyphenyl)thio]ethylmercury sodium salt
Sodium ethyl mercurithiosalicylate
Thiomersalate
Thimerosal
Thiomersal
Uses
Antiseptics
Antitoxins
Cosmetics
Eye preparations (contact lens solutions, eyedrops)
Skin testing antigens
Topical and systemic medicines (ear and nose drops, Tincture of Merthiolate)
Vaccines
Cross-Reactions
Unusual Reactions
References
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34. |
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35. |
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36. |
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37. |
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38. |
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39. |
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40. |
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41. |
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49. |
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08-01-2012
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