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CAS: Chemical Abstract Service Registry Number


Thiourea is used as a photographic fixing agent and stain remover. It is also used as a rubber vulcanizing accelerator.
Thiourea is used in the coating of diazo copypaper and plan printing paper ("blauwdrukpapier") to prevent oxidative yellow discoloration. 






Photocopy paper (diazo)
Rubber accelerator
Silver polish



Possible crossreactions may occur between Thiourea and
- Dibutylthiourea (DBTU, used in rubber gloves, diving shoes, diving suits, neoprene diving glasses, paint and glue removers, telephone cards, corrosion inhibitors in metal fluids.
- Diethylthiourea (DETU, used in rubber gloves and steunzolen, in neoprene afdichtstrippen, diving suits, diving glasses, brillenkoord and in rubber glue for shoes,. It is also used as an anti-corrosant in cleaning fluids.
- Dimethylthioureum (DMTU, used in textile patterns and plan printing paper ("blauwdrukpapier")
- Diphenylthiourea (DPTU, used in neoprene gloves, vulcan heat retainers, diving suits, orthopedic aids and in PVC plasters)
- Ethylbutylthioureum (EBTU, used in neoprene glue for shoes, diving suits, brillenkoord and in rubber steunzolen)
- Ethyleenthiourea (ETU, used in black fireman suits, rubber shoes, fungicides and anti-slimicides in the paper industry)


Unusual Reactions





Nurse, D.S., Sensitivity to thiourea in plan printing paper. Contact Dermatitis, 1980. 6(2): p. 153-4.


Roberts, J.L. and J.M. Hanifin, Contact allergy and cross reactivity to substituted thiourea compounds. Contact Dermatitis, 1980. 6(2): p. 138-9.


Kellett, J.K., M.H. Beck, and G. Auckland, Contact sensitivity to thiourea in photocopy paper. Contact Dermatitis, 1984. 11(2): p. 124.


Camarasa, J.G., et al., Thiourea reactivity in Spain. Contact Dermatitis, 1985. 12(4): p. 220.


Dooms-Goossens, A., et al., Contact and photocontact sensitivity problems associated with thiourea and its derivatives: a review of the literature and case reports. British Journal of Dermatology, 1987. 116(4): p. 573-9.


Dooms-Goossens, A., et al., Silver polish: another source of contact dermatitis reactions to thiourea. Contact Dermatitis, 1988. 19(2): p. 133-5.


Romaguera, C., et al., Contact dermatitis to thioureas. Contact Dermatitis, 1988. 18(3): p. 175-6.


Torres, V., et al., Occupational contact dermatitis to thiourea and dimethylthiourea from diazo copy paper. American Journal of Contact Dermatitis, 1992. 3(1): p. 37-39.


Kanerva, L., T. Estlander, and R. Jolanki, Occupational allergic contact dermatitis caused by thiourea compounds. Contact Dermatitis, 1994. 31(4): p. 242-8.


Leeda M, Bruynzeel DP. Contact-allergische reactie door thioureumverbindingen. Ned Tijdsch Dermatol Venereol 1998;8:293-297






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