Formula |
CAS |
C24H31FO6 |
76-25-5 |
CAS: Chemical Abstract Service Registry Number
Background
Triamcinolone acetonide is a high-potency topical and systemic corticosteroid.
It has been classified as group B by Coopman et al. According the A-D grouping,
patch-test reactions occur 6-7 times more frequently within well-defined
groups of structurally related chemicals than between corticosteroids of
different groups.
Synonyms
9-Fluoro-11,21-dihydroxy-16,17-[1-methylethylidenebis (oxy)]pregna-1,4-diene-3,20-dione
9a-Fluoro-11b,16a,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic
16,17-acetal with acetone
9a-Fluoro-16a-hydroxyprednisolone acetonide
Triamcinolone 16a,17-acetonide
9a-Fluoro-11b,21-dihydroxy-16a,17a-isopropylidenedioxy--1,4-pregnadiene-3,20-dione
9a-Fluoro-16a,17-isopropylidenedioxyprednisolone
Adcortyl-A
Aristoderm
Cutinolone Simple
Flutex
Ftorocort
Kenacort-A
Kenalog
Kenaquart
Ledercort D
Omcilon-A
Respicort
Rineton
Solodelf
Tramacin
Triamcinolone acetonide
Tricinolon
Vetalog
Volon A
Volonimat
Triamcinolone acetonide
Uses
Pharmaceuticals (injectable, topical)
Cross-Reactions
Amcinonide
Budesonide
Desonide
Unusual Reactions
References
1.
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Coskey, R.J.,
Contact dermatitis due to multiple corticosteroid creams.
Archives of Dermatology, 1978. 114(1): p. 115-7.
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2.
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Kark,
E.C., Sensitivity to fluorinated steroids presenting as
a delayed hypersensitivity. Contact Dermatitis, 1980. 6(3):
p. 214-6.
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3.
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Brambilla, L., et al.,
Allergic reactions to topical desoxymethasone
and oral triamcinolone. Contact Dermatitis, 1989. 21(4): p.
272-4.
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4.
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Coopman, S., H.
Degreef, and A. Dooms-Goossens, Identification
of cross-reaction patterns in allergic contact dermatitis from topical
corticosteroids. British Journal of Dermatology, 1989. 121(1):
p. 27-34.
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5.
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Rivara, G., R.R. Tomb, and J.
Foussereau, Allergic contact dermatitis
from topical corticosteroids. Contact Dermatitis, 1989. 21(2):
p. 83-91.
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6.
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Hayakawa, R., et al.,
Allergic contact dermatitis due to amcinonide.
Contact Dermatitis, 1990. 23(1): p. 49-50.
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7.
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Lepoittevin, J.P., J.
Drieghe, and A. Dooms-Goossens, Studies
in patients with corticosteroid contact allergy. Understanding cross-reactivity
among different steroids [see comments]. Archives of Dermatology, 1995. 131(1): p. 31-7.
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08-01-2012
(JRM) - www.huidziekten.nl
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