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Formula |
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CAS: Chemical Abstract Service Registry Number
Background
Wool is a natural protein fiber consisting mainly of protein, an
oily, waxy external lipid fraction and a minor internal lipid content.
hydrolysis of the external lipids result in a complex mixture of esters
of alochols and fatty acids of which wool alcohols (lanolin) are the main
allergen. Other alcohols like stearylalcohol, cetylalcohol and oleylalcohol,
may less frequently cause contact allergies. The composition of lanolin
varies based on time and place of manufacture. The sebum of sheep constitutes
5% to 25% of the weight of sheared raw wool.
Lanolin is used in cosmetic and pharmacologic preparations because
of its emollient, moisturizing, and emulsifying properties. Numerous chemical
modifications of lanolin are used to improve its attributes and eliminate
particular disadvantages.
Because lanolin is a complex natural product, the allergens have not
been definitively delineated. The wide variety and purity of lanolin make
complete identification of its components virtually impossible. Lanolin-sensitive
patients can sometimes tolerate one lanolin preparation but not another.
Lanolin allergy is most common among leg ulcer patients.
Synonyms
Anhydrous lanolin
Wool fat
Wool wax
Wool grease
Wool alcohol
Clearlin
Glossylan
Golden Dawn
Hychol
Nodorian
Sparklelan
Adeps lanae anhydrous
Aloholes lanae
Names for Modified Lanolin
Lanolin acid
Amerlate
Argowax
Facilan
Lanolic acids
Ritalafa
Skliro
Lanolin alcohol
Argo wax
Fancol LA
Hartolan
Lanalol
Nimco
Rita wax
Lanolin oil
Argonol
Fluilan
Lanalene
Lanogene
Lanoil
Lantrol
Lipolan
Ritalan
Vigilan
Lanolin wax
Albalan
Lanalene wax
Lanfrax
Lanocerin
Lanowax
Uses
Cosmetics- creams, lotions, ointments, etc.
Cutting oil emulsions
Furniture polish
Furs
Inks
Leather
Metal corrosion prevention
Paper
Textiles
Topical medications
Waxes
Cross-Reactions
Lanette wax
Unusual Reactions
References
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1. |
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2. |
Breit, R. and H.J. Bandmann, Contact dermatitis XXII. Dermatitis from lanolin. British Journal of Dermatology, 1973. 88(4): p. 414-6. |
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3. |
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4. |
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5. |
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6. |
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22. |
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26. |
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27. |
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29. |
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30. |
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31. |
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32. |
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33. |
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34. |
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35. |
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36. |
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37. |
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38. |
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39. |
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40. |
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41. |
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42. |
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43. |
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44. |
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13-08-2011
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